Standard

Menarche (age at onset)

FTO · rs9939609

Where this position leads

Condition: Age at Menarche

rs9939609 Condition: Age at Menarche Age at Menarche Condition Topic: Exercise and muscle Exercise and muscle Topic Topic: Weight-loss medicines Weight-loss medicines Topic Topic: Alcohol and the flush Alcohol and the flush Topic rs9939609 rs9939609 FTO

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Menarche (age at onset) compared to the general population. (GWAS Catalog, Nat Genet 2010, PMID:21102462)
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Menarche (age at onset). (GWAS Catalog, Nat Genet 2010, PMID:21102462)
T/T Published research associates this genotype with typical/baseline likelihood of Menarche (age at onset) — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2010, PMID:21102462)

Source: GWAS Catalog, Nat Genet 2010, PMID:21102462

What people read about alongside this

Exercise and muscle97 Weight-loss medicines8 Alcohol and the flush8 Running and endurance6 Sleep and insomnia5 Sport and performance5 Brain and memory4 Risk-taking and impulsivity3 Learning and focus2 Personality2 ADHD and attention2 Depression and stress2 Longevity and ageing2 Gut and food intolerance2 Smell and taste1

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs9939609

What is rs9939609?

rs9939609 is a single position in the genome, in or near the FTO gene. Published research associates it with menarche (age at onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9939609 linked to?

On MyGeneLog this position is linked to Age at Menarche. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs9939609?

Subjects that appear in the title or abstract of the same papers as this rsID include exercise and muscle (97 papers), weight-loss medicines (8 papers), alcohol and the flush (8 papers), running and endurance (6 papers), sleep and insomnia (5 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs9939609 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9939609 come from?

GWAS Catalog, Nat Genet 2010, PMID:21102462. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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