Continuously updated · last reviewed Sep 5, 2026
The same pharmacogenomics that sits on our condition pages, read from the other end. People rarely arrive asking about SLCO1B1 — they arrive having been prescribed a statin. Each page below collects what published guidelines say about one drug, names the genes involved, and links to the variants your own file would contain.
None of this is dosing guidance. Where a clinical guideline exists it is written for prescribers, and the pages say so. Nothing here is a reason to start, stop or change a medication.
The one entry here that is not about how a drug is handled once it is inside you. It is about whether it gets inside you at all — a medicine that tastes unbearably bitter to one child and merely unpleasant to another is a real adherence problem with a genetic explanation.
TAS2R38
See what the research says → ContraceptiveA case where two risks multiply rather than add. Estrogen raises clot risk on its own; in someone who also carries a thrombophilia variant the two compound.
F5
See what the research says → Alzheimer disease therapyHere genotype is used before treatment rather than to explain a reaction afterwards: APOE status predicts how likely a person is to develop brain swelling or small bleeds on these drugs.
APOE
See what the research says → AnalgesicOne of the most studied genes in all of pharmacogenomics sits here — and the guideline that reviewed it concluded that no dosing recommendation can be made. That conclusion is the finding.
OPRM1
See what the research says → Cholesterol-loweringAmong the most prescribed drugs in the world. Muscle symptoms are the leading reason people stop taking them, and stopping means losing the cardiovascular protection they were prescribed for.
SLCO1B1 · ABCG2 · CYP2C9
See what the research says → AnticoagulantAn anticoagulant with a narrow therapeutic index, whose effective dose differs several-fold between people. More of that variation is explained by genotype than for almost any other drug in common use.
VKORC1 · CYP2C9 · CYP4F2
See what the research says →