Sensitive

Lung cancer

CHRNA5 · rs8034191

Where this position leads

Condition: Lung Cancer

rs8034191 Condition: Lung Cancer Lung Cancer Condition Topic: Smoking and vaping Smoking and vaping Topic rs8034191 rs8034191 CHRNA5

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Lung cancer compared to the general population. (GWAS Catalog, Nature 2008, PMID:18385738)
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Lung cancer. (GWAS Catalog, Nature 2008, PMID:18385738)
T/T Published research associates this genotype with typical/baseline likelihood of Lung cancer — no copies of the reported risk allele. (GWAS Catalog, Nature 2008, PMID:18385738)

Source: GWAS Catalog, Nature 2008, PMID:18385738

What people read about alongside this

Smoking and vaping8 Alcohol and the flush2

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs8034191

What is rs8034191?

rs8034191 is a single position in the genome, in or near the CHRNA5 gene. Published research associates it with lung cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs8034191 linked to?

On MyGeneLog this position is linked to Lung Cancer. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs8034191?

Subjects that appear in the title or abstract of the same papers as this rsID include smoking and vaping (8 papers), alcohol and the flush (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs8034191 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8034191 come from?

GWAS Catalog, Nature 2008, PMID:18385738. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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