C/CPublished research associates this genotype with typical/baseline likelihood of Childhood obesity — no copies of the reported risk allele. (GWAS Catalog, Hum Mol Genet 2019, PMID:31504550)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Childhood obesity. (GWAS Catalog, Hum Mol Genet 2019, PMID:31504550)
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Childhood obesity compared to the general population. (GWAS Catalog, Hum Mol Genet 2019, PMID:31504550)
rs74583214 is a single position in the genome, in or near the GAS8 gene. Published research associates it with childhood obesity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs74583214 linked to?
On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs74583214 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs74583214 come from?
GWAS Catalog, Hum Mol Genet 2019, PMID:31504550. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.