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Atrial fibrillation

PHLDB2 · rs73228543

Where this position leads

Condition: Atrial Fibrillation

rs73228543 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs73228543 rs73228543 PHLDB2

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Atrial fibrillation — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2018, PMID:29892015)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Atrial fibrillation. (GWAS Catalog, Nat Genet 2018, PMID:29892015)
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Atrial fibrillation compared to the general population. (GWAS Catalog, Nat Genet 2018, PMID:29892015)

Source: GWAS Catalog, Nat Genet 2018, PMID:29892015

Questions about rs73228543

What is rs73228543?

rs73228543 is a single position in the genome, in or near the PHLDB2 gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73228543 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs73228543 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73228543 come from?

GWAS Catalog, Nat Genet 2018, PMID:29892015. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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