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Early onset atrial fibrillation

HAND2 · rs4615152

Where this position leads

Condition: Atrial Fibrillation

rs4615152 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs4615152 rs4615152 HAND2

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Early onset atrial fibrillation compared to the general population. (GWAS Catalog, Eur Heart J 2017, PMID:28460022)
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Early onset atrial fibrillation. (GWAS Catalog, Eur Heart J 2017, PMID:28460022)
T/T Published research associates this genotype with typical/baseline likelihood of Early onset atrial fibrillation — no copies of the reported risk allele. (GWAS Catalog, Eur Heart J 2017, PMID:28460022)

Source: GWAS Catalog, Eur Heart J 2017, PMID:28460022

Questions about rs4615152

What is rs4615152?

rs4615152 is a single position in the genome, in or near the HAND2 gene. Published research associates it with early onset atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4615152 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs4615152 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4615152 come from?

GWAS Catalog, Eur Heart J 2017, PMID:28460022. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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