A/APublished research associates this genotype with typical/baseline likelihood of Liver enzyme levels (alkaline phosphatase) — no copies of the reported risk allele. (GWAS Catalog, Nat Commun 2021, PMID:33972514)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Liver enzyme levels (alkaline phosphatase). (GWAS Catalog, Nat Commun 2021, PMID:33972514)
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Liver enzyme levels (alkaline phosphatase) compared to the general population. (GWAS Catalog, Nat Commun 2021, PMID:33972514)
rs35013847 is a single position in the genome, in or near the CYP2C19 gene. Published research associates it with liver enzyme levels (alkaline phosphatase). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs35013847 affect how medicines work?
CYP2C19 carries pharmacogenomic findings for Clopidogrel. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs35013847 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35013847 come from?
GWAS Catalog, Nat Commun 2021, PMID:33972514. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.