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Atrial fibrillation

MAPT · rs242557

Where this position leads

Condition: Atrial Fibrillation

rs242557 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs242557 rs242557 MAPT

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Atrial fibrillation — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2018, PMID:29892015)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Atrial fibrillation. (GWAS Catalog, Nat Genet 2018, PMID:29892015)
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Atrial fibrillation compared to the general population. (GWAS Catalog, Nat Genet 2018, PMID:29892015)

Source: GWAS Catalog, Nat Genet 2018, PMID:29892015

What people read about alongside this

Brain and memory1

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs242557

What is rs242557?

rs242557 is a single position in the genome, in or near the MAPT gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs242557 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs242557?

Subjects that appear in the title or abstract of the same papers as this rsID include brain and memory (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs242557 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs242557 come from?

GWAS Catalog, Nat Genet 2018, PMID:29892015. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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