G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Obesity compared to the general population. (GWAS Catalog, BMC Med Genomics 2011, PMID:21708048)
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Obesity. (GWAS Catalog, BMC Med Genomics 2011, PMID:21708048)
T/TPublished research associates this genotype with typical/baseline likelihood of Obesity — no copies of the reported risk allele. (GWAS Catalog, BMC Med Genomics 2011, PMID:21708048)
Source: GWAS Catalog, BMC Med Genomics 2011, PMID:21708048
Questions about rs2116830
What is rs2116830?
rs2116830 is a single position in the genome, in or near the KCNMA1 gene. Published research associates it with obesity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2116830 linked to?
On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs2116830 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2116830 come from?
GWAS Catalog, BMC Med Genomics 2011, PMID:21708048. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.