Sensitive

Alzheimer's disease (late onset)

APOE · rs2075650

Where this position leads

Condition: Alzheimer's Disease Risk (APOE)

Drug: Lecanemab and other anti-amyloid antibodies

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Alzheimer's disease (late onset) — no copies of the reported risk allele. (GWAS Catalog, PLoS Genet 2010, PMID:20885792)

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Alzheimer's disease (late onset). (GWAS Catalog, PLoS Genet 2010, PMID:20885792)

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Alzheimer's disease (late onset) compared to the general population. (GWAS Catalog, PLoS Genet 2010, PMID:20885792)

Source: GWAS Catalog, PLoS Genet 2010, PMID:20885792

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