Sensitive

Restless legs syndrome

MAP2K5 · rs12593813

Where this position leads

Condition: Restless Legs Syndrome

rs12593813 Condition: Restless Legs Syndrome Restless Legs Syndrome Condition rs12593813 rs12593813 MAP2K5

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Restless legs syndrome — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2007, PMID:17637780)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Restless legs syndrome. (GWAS Catalog, Nat Genet 2007, PMID:17637780)
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Restless legs syndrome compared to the general population. (GWAS Catalog, Nat Genet 2007, PMID:17637780)

Source: GWAS Catalog, Nat Genet 2007, PMID:17637780

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs12593813

What is rs12593813?

rs12593813 is a single position in the genome, in or near the MAP2K5 gene. Published research associates it with restless legs syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12593813 linked to?

On MyGeneLog this position is linked to Restless Legs Syndrome. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs12593813?

Subjects that appear in the title or abstract of the same papers as this rsID include adhd and attention (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs12593813 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12593813 come from?

GWAS Catalog, Nat Genet 2007, PMID:17637780. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants