A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Obesity compared to the general population. (GWAS Catalog, Nat Genet 2013, PMID:23563607)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Obesity. (GWAS Catalog, Nat Genet 2013, PMID:23563607)
G/GPublished research associates this genotype with typical/baseline likelihood of Obesity — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2013, PMID:23563607)
rs11639988 is a single position in the genome, in or near the GPRC5B gene. Published research associates it with obesity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11639988 linked to?
On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs11639988 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11639988 come from?
GWAS Catalog, Nat Genet 2013, PMID:23563607. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.